Cancer's molecular sweet tooth and the Warburg effect.
نویسندگان
چکیده
More than 80 years ago, the renowned biochemist Otto Warburg described how cancer cells avidly consume glucose and produce lactic acid under aerobic conditions. Recent studies arguing that cancer cells benefit from this phenomenon, termed the Warburg effect, have renewed discussions about its exact role as cause, correlate, or facilitator of cancer. Molecular advances in this area may reveal tactics to exploit the cancer cell's "sweet tooth" for cancer therapy.
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عنوان ژورنال:
- Cancer research
دوره 66 18 شماره
صفحات -
تاریخ انتشار 2006